Internal event (Department/Institute)
Module Clinical Reality
Participants will learn how specific inborn errors of immunity affect the immune system and how certain drugs used in the treatment of diseases can cause unintended immune dysfunctions.
Dysfunction of the immune system and therapeutic options
Participants will first receive a brief overview of the cellular components of the immune system and its strategies and mechanisms used to prevent the spread of pathogens and their products. This will include a summary of the organization of the immune system, its strategies for responding to pathogens, and the major cellular components of innate and adaptive responses. Participants will learn how specific inborn errors of immunity affect the immune system and how certain drugs used in the treatment of diseases can cause unintended immune dysfunctions.
Case studies highlighting different aspects of immune response in the context of increased susceptibility to infections as well as increased risk of immune dysregulation are presented. Participants will learn about diagnostic approaches including functional assays, flow cytometry and genetics. Treatment options are presented including immunoglobulin therapy, Jak-inhibitors and other immunosuppressive medications.
09.00 – 10.00 Seminar: Brief overview of the cellular components of the immune system and their role in the human body
10.00 – 11.00 Seminar and Visit to the Clinic: Dysfunctions of the immune system in cancer patients
11.00 – 11.15 Short Break
11.15 – 12.45 Seminar: Inborn errors of immunity – from symptoms to diagnostics to treatment
12.45 – 14.00 Lunch Break
14.00 – 15.30 Seminar: Immunology and Transplantation
For optimal comprehension, students should have an entry-level understanding of molecular and cellular biology - with emphasis on gene expression, protein synthesis, signalling molecules and cellular receptors.
Organizational and administrative matters
17.11.2023: 09:00 - 15:30